About

Dr. Chris DeRienzo is a dedicated husband, a proud father, a mediocre triathlete, and author of the multi-category #1 Best Seller Tiny Medicine: One Doctor’s Biggest Lessons from His Smallest Patients (available in paperback).  He’s also a physician committed to improving America’s health, a frequent keynote speaker, and an advisor to companies ranging from early stage to the Fortune 50.

Recognized by Modern Healthcare, Becker’s, and Triangle Business Journal, Dr. DeRienzo loves bringing together the people, process and technology needed to drive transformation. He currently serves System Chief Medical Officer and SVP of WakeMed Health & Hospitals, where he leads the system’s Clinical Transformation portfolio and is a practicing neonatologist. Outside WakeMed, Chris serves on Board Committees / Board Advisory Councils for Premier, Inc. (NASD: PINC), the American Hospital Association, and Mercy Health (Chesterfield, MO).

Chris’s previous roles include serving as Chief Quality Officer for Mission Health, a $2B non-profit health system formerly based in Asheville, NC.  His leadership there helped infuse data-driven, analytics-enabled transformation throughout the organization, propelling Mission back to recognition by IBM Watson as a Top 15 Health System in both 2017 and 2018.  He also served as Chief Medical Officer of AI-based company Cardinal Analytx, where he led the company’s clinical and health economics portfolios through a period of significant growth and a $22 million funding round.

Chris lives with his family, two incredibly energetic dogs, and an ever-expanding flock of chickens in North Carolina.

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