About Chris

Dr. Chris DeRienzo is a dedicated husband, a proud father, a mediocre athlete, and author of the multi-category #1 Best Seller Tiny Medicine: One Doctor’s Biggest Lessons from His Smallest Patients (also available in Paperback).  He’s also a physician committed to improving America’s health, a frequent keynote speaker, and an advisor to companies ranging from early stage to the Fortune 50.

Recognized by Modern Healthcare, Becker’s, and the Triangle Business Journal as one of healthcare’s “Rising Stars,” Dr. DeRienzo loves bringing together the people, process and technology needed to drive exponential transformation. He currently serves System Chief Medical Officer and SVP of WakeMed Health & Hospitals, where he leads the system’s Clinical Excellence portfolio and is a practicing neonatologist. Outside WakeMed, Chris serves as a Senior Scholar in the Stanford University Clinical Excellence Research Center, and a Board Advisor to both Premier, Inc. (NASD: PINC) and Mercy Health (Chesterfield, MO).

Chris’s previous roles include serving as Chief Quality Officer at Mission Health, a $2B integrated health system based in Asheville, NC.  His leadership there helped infuse a data-driven, analytics-enabled culture of continuous improvement throughout the organization, propelling Mission back to recognition by IBM Watson as a Top 15 Health System in both 2017 and 2018.  He also previously served as Chief Medical Officer of AI-based company Prealize, where he led the company’s clinical and health economics portfolios through a period of significant growth and a $22 million funding round.

Chris lives with his family, two incredibly energetic dogs, and an ever-expanding flock of chickens in North Carolina.