Tiny Medicine – Available Now!

Tiny Medicine is an important book and should be required reading for everyone in the healthcare field … it inspires us with real-world examples of humanity’s hope, perseverance, dedication, and hope.”

—Eric Langshur, New York Times Bestselling Co-author of Start Here: Master the Lifelong Habit of Wellbeing

Dr. Chris DeRienzo

“By lifting the shield that protects his heart, Dr. DeRienzo provides a rare glimpse into what it means to be both human and a doctor. He proves that as physicians we do not have to check our souls at our patients’ doors, and his stories give readers hope that healthcare can be healed.”

—Dr. Bridget Duffy, CMO Vocera Communications, Inc.


“We had Chris speak as a keynote at one of our conferences. His talk was loved by our audience. He is a complete professional and made sure to communicate before and after the meeting to ensure he fit the needs of our conference.   He is a great speaker!” 

-Scott Becker, Founder and Publisher of Becker’s Healthcare Media

“Dr. Chris’s presentation was passionate, heartwarming, and motivating.”

“Tying in his experiences with one of his patient’s made his story particularly memorable and engaging.”

“He reinforced the concept that we are good today, but our goal is to be better tomorrow.”

About Chris

Dr. Chris DeRienzo is a dedicated husband, a proud father, a mediocre triathlete, and author of the Amazon Best Seller Tiny Medicine: One Doctor’s Biggest Lessons from His Smallest Patients (Big Eye Books).  He’s also a physician committed to improving America’s health and striving to match Theodore Roosevelt’s efforts to live life as a spectacle of the human engine driven at full speed.

Chris currently serves as Chief Medical Officer for Cardinal Analytx Solutions and as an Adjunct Professor of Population Health with Stanford University’s Clinical Excellence Research Center.  Prior to joining CAS, Chris served as Chief Quality Officer for Mission Health, formerly a $2B integrated delivery system based in Asheville, NC.  In this role, he had senior executive responsibility for quality, safety, experience, analytics and population health across Mission’s inpatient, ambulatory, and post-acute enterprise.  His leadership helped infuse Mission with a data-driven, analytics-enabled culture of continuous improvement, propelling the system back to recognition by IBM Watson as a Top 15 Health System in both 2017 and 2018.

Recognized by Modern Healthcare in 2018 as one of 15 “Up and Comers” Under 40 and Becker’s as one of healthcare’s “Rising Stars,” Chris has published and presented internationally on leveraging analytics to drive continuous improvement, implementing data science in healthcare, and the intersection of humanity and technology.  A frequent keynote speaker and the first ever HIMSS SPARK (TED-style) Speaker, he also advises both state and national governments and companies from early-stage to the Fortune 500 and volunteers as a member of the Mercy Health (Chesterfield, MO) Board Quality Committee and the YMCA Blue Ridge Assembly Board of Directors.

Board Certified in both Pediatrics and Neonatology, Dr. DeRienzo completed his M.D., Masters in Public Policy, and post-graduate medical training all at Duke.  At a national level, Dr. DeRienzo was just the fourth medical student elected and re-elected to serve on the AMA Board of Trustees. He is a Past-President of the Durham-Orange County Medical Society and has served in leadership roles within the American Academy of Pediatrics and the North Carolina Medical Society.  He was appointed in early 2018 by the North Carolina Secretary of Health and Human Services to serve on the Medical Care Advisory Committee, advising the Department on all aspects of Medicaid transformation, and has spent time advising the NC Quality Center on Safety Culture, the NC Division of Public Health, and the NC Institute of Medicine.

Outside of work Chris enjoys competing in triathlon.  He finished his first Ironman race in Louisville in 2018, is a two-time Ironman 70.3 Finisher and has twice raced at the USA Triathlon Olympic Distance Age Group National Championships.  He’s also a sucker for bucket list races his friends convince him “really won’t be as hard as they sound” and a frequent early-morning Zwift rider.  He’s seen every episode of The West Wing at least twice and can quote “Two Cathedrals” line-for-line… including the Latin swearing.

Chris lives with his family and their two incredibly energetic dogs in Asheville, NC.


To get in touch with Chris for speaking engagements, book events, media inquiries, consulting requests, or just to say hi, please use the form below: